WELCOME TO THE FATATIS LABORATORY
The vast majority of patients with advanced cancers of the prostate and breast eventually succumb to metastatic disease. Our laboratory is focused on understanding the cellular and molecular factors implicated in metastasis and identifying novel and effective therapeutic targets to decelerate or arrest the emergence and progression of metastatic tumors.
Worrede A, Meucci O, Fatatis A. Limiting Tumor Seeding as a Therapeutic Approach for Metastatic Disease. Pharmacology & Therapeutics. (2019)
Qian C, Worrede-Mahdi A, Shen F, DiNatale A, Kaur R, Zhang Q, Cristofanilli M, Meucci O, Fatatis A. Impeding Circulating Tumor Cell Reseeding Decelerates Metastatic Progression and Potentiates Chemotherapy.
Molecular Cancer Research. 16, 1844-1854, (2018)